Cracking the Genetic Code: Genomic Science and Bioethics

Thanks, I suppose, to my friends Joshua Boger ’73 and Joe Fins ’82, I joined the board of the Hastings Center last year. At our last meeting, we saw a film that Hastings consulted on with PBS’s NOVA. It has to do with the tremendous advances in genomic science, and the ethical issues that have arisen as the clinical applications of the science become more accessible. Wesleyan’s strengths in science studies are really formidable, and some of those strengths fall into the bioethics category. The Science and Society Program, Feminist, Gender and Sexuality Studies, the Center for the Humanities, the Sociology, History and Philosophy departments are just some of the areas where one can find sophisticated work on bioethics at Wesleyan. And in throughout the life sciences at Wes, one can find advanced work that depends on genomics.

I put his up today on the Huffingtonpost.

On Wednesday, March 28th (9 p.m./8c), PBS will broadcast an important film that explores some of the crucial ethical issues that are emerging from the life sciences: how to use our knowledge of personal genetic information; and who should have access to this information about our individual and familial genetic data? On the one hand, genomic science promises us an unprecedented look at the material sources of our lives, and on the other hand, this science may tempt some to think that we are nothing more than our genetic makeup.

Cracking Your Genetic Code is a joint project of PBS’s NOVA producers and the Hastings Center, a bioethics research center on whose board I sit. The film gives an insightful and moving portrait of how people who suffer from genetic disorders are investing their hopes in genomic science. Designer drugs, like those to combat some forms of cystic fibrosis, are shown to have enormous potential for patients who can get access to them early enough to reverse the ravages of disease. In addition to the patients’ stories, we hear from scientists eager to use their understanding of the genetic bases of disease to prevent symptoms from emerging in future generations. Francis Collins, director of the National Institutes of Health, is particularly compelling as he describes the clinical potential of genomic medicine.

Cracking Your Genetic Code also describes the more troubling potential in our new understanding of our biological heritage. Will we want to know if our genes make it likely that we will develop a life threatening or debilitating disease? Will we want to tell our children, and, if so, when? Will the knowledge be helpful, or just a burden? Who else will know about our genetic destiny? Insurance companies? Advertising firms?

The Hastings Center’s Help With Hard Questions website provides a useful way of navigating in the new world opened up by contemporary genomic science. NOVA, too, has a website that complements the film. Both use social networking to bring together people concerned about what to do with the new knowledge that is available to us through science and technology.

It was not long ago that the goal of cracking the genetic code seemed like a wild ambition. Soon we will be able to get our own personalized genetic information almost anywhere for under $1000. The information tells us about our biological constitution; how will we relate that to our sense of self, family and destiny? Cracking Your Genetic Code raises more questions than it answers — perfectly appropriate as we strive to understand how to use and to protect these new modes of knowledge.

Here’s a clip from the film:

 

New Year’s Eve in Middletown: Main Street Celebration!

Thanks to Mark Masselli (Hon ’09, P ’15, P’16), Community Health Center and a group of dedicated sponsors (Wesleyan included), there is going to be a great new tradition starting in Middletown on December 31st. Midnight on Main promises to be a great family-friendly event starting at 3 PM and ending with tolling of the bells as the year turns. There are more than a 100 events up and down Main Street. A fireworks extravaganza is planned for 6 PM.

For more information about Midnight on Main, check out this website.

UPDATE: NEW YEAR’S DAY

(photo from middletowneye)

 

It was great to see the happy crowds wandering around Main Street around the time of the stupendous fireworks display. All the restaurants were filling up, as were the many shows that were attracting folks from all over Central Connecticut. As I walked back up Washington Street to campus, I saw smiling groups emerging from Kidcity Children’s Museum. I was reminded of the museum’s founding director Jennifer Alexander’s (‘ 88, Hon ’09, P ’15, P’16) important work here in Middletown for over 20 years. It was wonderful to see Mark’s and Jen’s vision for Midnight on Main turn into such a successful even last night. Happy New Year!!

 

Coming Home, Finding Family

The extended Wes family has gathered together this weekend, celebrating scholarship, athletics, teaching and all things Red and Black. The seminars were often full and always lively, and they brought together the great energy that characterizes the classes here. I ran into Orin Snyder  ’83, who had just come from a packed discussion, led by the Wesleyan Lawyers Association, of the changing legal network for social media. And Alberto Ibarguen ’66 P’97 HON’11 was equally enthused about his session celebrating 50 years of the Peace Corps. The history of the Peace Corps at Wesleyan spills naturally into our new PATRICELLI CENTER FOR SOCIAL ENTREPRENEURSHIP. We cut the ribbon on the new Center on Saturday morning. Later in the day on Saturday I ran into some starry-eyed parents who were quite in awe of the presentation by Wes film faculty Jeanine Basinger, Scott Higgins and Steve Collins on “what makes movies great”! Jeanine was quoted extensively in this morning’s New York Times on Leonardo diCaprio (and a few days ago could be found in the Wall Street Journal). Our film folks are everywhere, but there’s nothing like seeing them on the home turf!

This weekend saw a grand celebration of the extraordinary work in experimental music by Alvin Lucier. Lucierfest brought out artists, musicians and writers who have been inspired by this pioneering composer and teacher. And speaking of things musical, I was delighted to catch Randy Newman’s benefit performance in the chapel on Friday night. We veered from ironic complicity to emotional commitment as he sampled his catalogue.

The efforts of our student athletes were so impressive this weekend, even if they left us saying, “wait ’til next year!” The cross country teams had very strong showings: the women were 6th of 40 teams  and the men were 9th of 44 teams. The women’s soccer team played well but fell to Amherst in the semi-finals of the NESCAC tournament. Our great goalie Jess Tollman ’15 kept the Lord Jeffs at bay for the first half, a fitting end to her strong first year. Our star forward Laura Kurash ’13 was named District Academic All American. This was our first time advancing this far in the tournament, and we are very proud of the women who battled all semester.

And speaking of a battle…our football team put up a mighty effort against the Purple Ephs in front of an enthusiastic homecoming crowd. We came very close to pulling off a great upset against Williams, thanks to a strong team effort. Matt Coyne passed for 192 yards, and star freshman running back LaDarius Drew ’15 was a workhorse despite the cast on his injured hand. Seniors Brett Bandazian and Jordan Greene had 10 tackles apiece, and our punter Jesse Warren ’15 had a world-class game. Coach Mike Whalen ’83 and the entire team are working together to build a great program. We are very proud of them!

All our athletes today are inspired by the great achievements of Wes students in the past. On Saturday night we inducted an all-star group into the Wesleyan Athletics Hall of Fame. When Moira James ’78, along with Dennis Robinson ’79 and the Athletics Advisory Council, came up with the idea of the hall of fame, I knew it would be a way of recognizing and reconnecting with our alumni greats. They also probably figured it would inspire contemporary success. And they were right!

I wish I were able to attend all the events, and it’s been a joy to welcome so many back to campus after a challenging week. Go Wes!

 

Late Afternoon A Cappella
Late Afternoon A Cappella

UPDATE: What a great thing to hear the many a cappella groups at the First Annual Stone A Capella Concert, celebrating Chip Stone ’49, p’79, P’82, GP ’11, GP ’15. A highlight for us was Chip and daughter Sarah Stone Maynard ’79 P ’11 singing a duet about the dangers of drugs to start things off.

 

Traveling with the Liberal Arts Message

I’ve been on the road for the last several days, visiting the University of California at Berkeley’s Townsend Humanities Center to give two lectures.

http://townsendcenter.berkeley.edu/publicworld_roth.shtml

http://townsendlab.berkeley.edu/critical-theory/events/michael-roth-trauma-shame-photography-guilty-thoughts-emotional-teacher

The first had to do with the long tradition of liberal arts education in the United States, and how we must defend and reinvigorate that tradition today. The second was based on my my scholarly work on photography and critical theory, with particular attention to how one might face pedagogical challenges in contexts in which affect is running very high. These were filmed, so they should be on the web soon.

I had the opportunity to visit the California College of the Arts campus in San Francisco. It’s a high energy place, and I was so pleased to feel the vibrancy of the work on architecture, design, and art that I saw displayed.

CCA in San Francisco

I visited with some alumni while in the Bay Area, and several Wes folks came out to UC to hear the talks. It was great to see them!

I am now in Bejing to participate in a colloquium on Tradition co-sponsored by Wesleyan and the Social Science in China Press.

Our philosophy of history journal History and Theory has spearheaded this joint program, with great leadership from Professors Steve Angle and Ethan Kleinberg. It’s my first trip to China, and though it will be very short, I’m looking forward to building ongoing relationships with our colleagues here. I’m also giving a lecture at Beijing Normal University on why liberal arts matter and will get together with alumni before heading home. I have to be ready for class on Monday!

Occupy Wall Street and Education

Students have asked me about how I feel about the protests going on under the banner of Occupy Wall Street. I know several who have been participating in New York, and others who plan to join in during the fall break just about to begin.  Today I posted the following piece on the Huffington Post.

 

The Occupy Wall Street protests have become an important topic on college campuses. At Wesleyan, some of our students have joined the group in Zuccotti Park in New York, and others have found a variety of ways of expressing their support. Given the mainstream media’s treatment of the movement, it’s easy to mock the lack of clear policy initiatives or to roll one’s eyes at the absence of leaders to express a neat list of demands. But in talking with students and reading some of the statements from the Occupy Wall Street participants, it seems to me that we get a pretty clear picture of their discontent. Like many Americans, they are revolted by how huge infusions of money are corrupting our political system. And, they are aghast at the trajectory of increasing inequality.

There is plenty to protest. There is no question that our politicians now spend enormous amounts of time raising money; we all get the robocalls and the junk mail to prove it. And there is little doubt that elected officials make decisions about particular legislation or policy initiatives while considering how those decisions will affect the willingness of their donors to contribute. At least in this way, money is eating away at our increasingly dysfunctional political system. This is not something that other representative democracies accept as a necessary part of politics. We can try to show how the money flows – that’s been one of the tasks of the Wesleyan Media Project – but we don’t stem the tide.

Meanwhile, economic inequality in the country is accelerating in frightening ways. Here are three representative facts from Nicholas Kristof’s column from last Sunday’s New York Times:

The 400 wealthiest Americans have a greater combined net worth than the bottom 150 million Americans.

The top 1 percent of Americans possess more wealth than the entire bottom 90 percent.

In the Bush expansion from 2002 to 2007, 65 percent of economic gains went to the richest 1 percent.

Add to this that in many parts of the country 1 in 5 children are growing up in poverty, and you begin to have a sense of what is fueling the anger of protestors who feel they have to “occupy” public spaces in their own country – a country they feel is being stolen from them.

How have these trends concerning money and inequality affected life on a university campus? We can see it at either end of the college experience, beginning with access and ending with jobs after graduation. More of our students need financial aid than ever before, and they often need bigger scholarship packages to get through school. We also see the effects of rising inequality in the choices students face when looking for jobs as graduation nears. They hope to have had practical internship experiences to bolster their resumes while undergraduates, and they often worry that the first job they get after college will set them in an income bracket that will frame them for life. They worry that if their education doesn’t seem like job training, then it isn’t education at all.

But in the campus’s classrooms, concert halls, theaters and sports facilities, I see little evidence of the pernicious economic-political trends poisoning the country at large. That’s because the educational enterprise assumes a core egalitarianism linked to freedom and participation; that’s because as teachers we are committed to equality of opportunity for our students and to their freedom to participate as they wish in the educational enterprise. In big lecture halls, students can’t buy the best seats or arrange for extra help sessions with their parents’ checkbooks. In small seminars, there is a face-to-face equality altered only by the talent, ambition and creativity of the discussion participants. Differences often quickly emerge, but these are the differences of performance —  variations able to emerge exactly because of the environment of equality and freedom.

As a university president, I do spend a lot of my time fundraising. And I am grateful for the generosity of alumni and foundations who support our financial aid and academic programs. But I am also a professor, and this support has no impact on my teaching role or on the role of my colleagues in the classroom.  Now I know that this will strike some readers as impossibly idealistic.  After all, some of our students  have had great help along the way, while others have had to struggle alone. Some come from wealthy families, others from backgrounds of poverty. There is  no doubt that some students are better prepared than others, and that some of that preparation was facilitated by wealth. Still, in the campus culture at schools like Wesleyan, these advantages of birth or luck don’t mean much over time. In order to learn, you have to park your privilege at the classroom door. In order to teach effectively, we try to ensure that our students have an equality of opportunity that doesn’t erase their differences. Furthermore, in those schools that have protected the autonomy of professors, students come to see intellectual freedom modeled by their instructors in ways not dependent on wealth.

When inequality is a charged political problem, as it is right now in the United States, it is because efforts to scale back disparities of wealth are seen as an assault on freedom.  Increased state power is often needed to redistribute wealth, and many (and not only those with the money) see this as the growth of tyranny. Of course, increased state power is also used to protect wealth, which creates its own assaults on freedom. Universities and colleges are lucky insofar as they still have an ethos of equality that is linked to freedom in the classroom and around campus. You don’t need strong central power to ensure this. That’s why efforts to control speech with university regulations, are rightly seen (by either the Left or the Right) as anathema to the educational enterprise.  But graduation into a world in which inequality is ever more powerful comes as a rude awakening.

The campus as a place of equality and freedom has deep roots in America, at least as far back as Thomas Jefferson.  Even with all his prejudices, he favored education at the public expense to prevent the creation of permanent elites based on wealth who would try to turn the government’s powers to their own private advantage. Jefferson believed strongly that given the variability in human capacities and energy there would always be elites —  his notion of equality was an equality of access or opportunity not an equality in which everybody wins. But he also believed strongly that without a serious effort to find and cultivate new talent, the nation’s elites would harden into  an “unnatural aristocracy,” increasingly privileged, corrupt and inept.

From Jefferson to our own day, we have preserved the belief that education allows for the experience of freedom as one’s capacities are enhanced and brought into use. The author of the Declaration of Independence wanted university students to make these discoveries for themselves, not to be told to study certain fields because their futures had already been decided by their families, teachers, churches or government. Jefferson saw education as a key to preventing permanent, entrenched inequality.

Citizens are feeling they have to “occupy” the public spaces of their own country because they believe their land is being appropriated by entrenched elites. The call to “occupy”  is very similar to the Tea Party cry to “take back” our country. Can we find a way to take the experiences of freedom and equality we find in education at its best and translate them to the sphere of politics and society more broadly without at the same time increasing governmental tendencies toward tyranny? Of course, higher education has its own dilemmas of fairness and of elitism, but that does not absolve us of the responsibility to connect in positive ways what we value in research and learning to our contemporary political situation.  To make these connections productive, universities must at the very least serve as models: they must continue to strive to be places where young people discover and cultivate their independence and must themselves resist the trends of inequality that are tearing at the fabric of our country.


Wes Trustee Joshua Boger in Biotech Hall of Fame

Yesterday I had my final conference call of the fiscal year with Wesleyan’s Board of Trustees. This devoted group of alumni and parents help steer the university for the long haul, and they find time in their busy schedules to provide support, critique and financial assistance for key Wes priorities. I am so grateful for their efforts.

The Board of Trustees is led by Joshua Boger ’73, P’06, P’09. A philosophy-chemistry major here as an undergraduate, Joshua has had an extraordinary career as a scientist, entrepreneur, philanthropist and citizen.  Recently he was recognized for his work in biotechology and chemistry. He  received the Lifetime Achievement Award from the Boston Biotech CEO Conference.  Shortly after this honor, a large international gathering in Washington D.C. presented him with  the Biotechnology Heritage Award, jointly given by BIO and the Chemical Heritage Foundation (non-profit keepers of the history of chemistry, located in Philadelphia).  This means that Joshua is a member of a very small and distinguished group known as the Biotechnology Hall of Fame.

Joshua Boger

Congratulations, Joshua!

 

Digital Media Alumni Shaping the Future

Last night I attended a terrific event in New York City with a large group of alumni working in the digital media sphere. We gathered at ZelnickMedia, and Strauss Zelnick ’79, Jim Friedlich ’79 and Andrew Vogel ’95 were great hosts to the more than 100 entrepreneurs. John Borthwick ’87 and Andy Weissman ’88 from Betaworks were helping with the hosting duties, and I learned about their entrepreneur-in-residence program. Now that’s something we could use at Wes! Imagine how many good ideas are bubbling up on campus, and how an enterprise builder might tease them out into some sustainable forms…

It was terrific to feel the energy of this crowd of inventive, ambitious alumni. I ran into my old friend Jane Polin ’80 and met Julie Burstein’80, whose recent book, Spark: How Creativity Works, is getting a lot of attention. There were folks from the venture capital field, like Stuart Ellman ’88, and Brad Burnham ’77, who were pretty much surrounded by eager alums with new ideas. Another giant in that field, Fred Wilson P’13, wrote his blog this morning about the confluence of science and art, and I can’t help but think he was inspired by some of the people he saw at the Wes reception. Recent grads (like Dina Kaplan ’93) were there as well as current student interns (like Benjamin Resnick ’13) and some senior media people, too, like Bill Blakemore ’65. Jake Levine ’08, as the lead volunteer heading the Wesleyan Digital Media effort, helped bring this all together.

I spoke briefly about the ways in which Wesleyan has been a pioneer in liberal education for more than 50 years. While other schools are playing defense or fighting over preserving turf boundaries, Wesleyan remains dedicated to expanding the boundaries of liberal learning. We believe that the liberal arts are INCREASINGLY relevant in an age of rapid technological transformation. We embrace the challenges of creating new networks of learning and positive social change. It was clear to me again last night in New York that our alumni are building on their Wesleyan education to shape the culture and economy of the future.

Go Wes!

Photos courtesy of Jake Levine ’08

Celebrating Wesleyan Music

At the end of last week I was in New York City with a great group of Wesleyan alumni to celebrate the long tradition of musical innovation at Wesleyan. We gathered at the Thalia Café to salute Mark Slobin, whose book, Music at Wesleyan: From Glee Club to Gamelan was published last year by Wesleyan University Press.

 

The evening was great fun, and it followed the trajectory of the book. A subset of the Cardinal Sinners were up first. This women’s a cappella group started us off with the beautiful alma mater, and their set also included a Bob Dylan tune. As a long-time Dylan diehard, I was just delighted. The singers were followed by a great experimental trio of bassoon, saxophone and percussion. The group started from an Anthony Braxton composition, and took off.

 

The Gamelan closed the evening with beautiful sounds both serene and uplifting. Alumni joined newly named University Professor Sumarsam in an all-star group of devoted players.

Thanks to Mark Slobin and all who attended. I almost forgot, you can get a copy of Music at Wesleyan (it makes a great gift!) here.

Reunion, Departures and… RETURN for Summer Sessions

Reunion/Commencement weekend is already becoming a blur in my memory as I think about all the alumni we welcomed back to campus, and the members of the class of 2011 that we sent off. So many people told me that the campus looked great, and I want to thank the Physical Plant staff for having worked tirelessly to keep things looking sharp. The University Relations crew managed the logistics with spirited grace, and I am so thankful for their efforts! From Faculty Marshalls to student workers, everybody pulled together.

Each year I take special pleasure in meeting with members of the class celebrating its 50th reunion, and 2011 was no exception. Bob Patricelli (who along with his wife, Margaret, received a Baldwin Medal for outstanding service) was the master of ceremonies at the reunion dinner, at which the class of 1961 made resounding clear why Wes has been known as “the singing college of New England.”

I had a little too much fun at the 25th Reunion dinner joining some of the musicians for a Class of ’86 blues.

I was really getting carried away — but then I realized there were real singers in the room, like Tierney Sutton and Dar Williams’89. Oy!

Spending time with our doctoral honorees was deeply gratifying. Biff and Jean Shaw shared words of wisdom about the power of community and the importance of service. Alberto Ibarguen added immeasurably to the weekend with his comments on the changing role of communication, and on how our grads might make their way through these revolutionary times. Paul Farmer was smart (expected) and really funny (an added treat) in his address to the class of 2011. I’ve admired Paul’s work for years, and it was delightful to see him engage with our students and faculty. Finally, I got to spend time with Barbara Cook, a singer who has brought joy, tears and passion to audiences for decades. It’s a little dangerous to finally get the chance to meet someone you idolize, but in this case it was pure pleasure.

I was impressed with all those who crossed the podium. As luck would have it, a good part of my commencement address was published on CNN.com over the weekend. Families came from far and wide to celebrate with their new graduates, and it is always bittersweet to say goodbye at the end of the festivities. But we will be start up again May 31 with summer session classes starting next week. If you want a dose of Wes magic in June, there is still room in some of the classes.

Shasha Seminar: Exploring Histories of Race

Each year Wesleyan hosts the Shasha Seminar for Human Concerns, bringing together scholars, students, faculty and alumni in an intensive series of lectures and discussions. Past programs have focused on popular culture, on environmentalism, on ethics and on international problems of violence. I remember the series of talks on food, which really made me think more carefully about the intersection of politics and economics on my kitchen table. And Joss Whedon’s 2009 discussion of how film and TV projects get made was funny and insightful. This year’s Shasha program, which runs from April 8-10, will explore ideas of race and how they have evolved over time.

Ideas concerning race have a long history, and it’s a history that continues to have powerful reverberations on politics and culture today. The organizer of the program, Andrew Curran of Romance Languages at Wes, has written on the history of the idea of race in relation to concepts of human origins, with a particular emphasis on the age of Enlightenment. The keynote speaker, Nell Painter, Honorary ’96, who for many years was a distinguished member of the history department at Princeton, has written the influential The History of White People, which will be the basis for her remarks on Saturday night. A leading historian of the United States, Prof. Painter is also an accomplished artist. Other discussions will explore race and science, the vicissitudes of race-thinking in Latin America and in China, and the ways that the idea of race still affects our conception of the human.

The Shasha Seminar offers a distinctive way of diving deep into a timely subject area in the company of curious, thoughtful and engaged participants. Alumni and parents join with students and outside experts to create an exceptionally lively series of conversations. If you are interested in learning more about the program, or in signing up for it, you can find information here.